The objective of this study was focused on the change fo the surface area and the skin thickness after full expansion of the skin of 4 female pigs with 300cc round shaped tissues expanders for 6 weeks.
The following is the method of experiment.
At first we shaved the backs of 4 female pigs by diameter 15cm sized round and tattooed one by diameter 9cm round and by reqular square of 4cm. One determined the control group and the other determined the expanded group. and we put 300cc round shaped tissue expander on them of the expanded group. We have injected 50cc normal saline a week and fully expanded for 6 seeds.
At 6 weeks when we have finished fully expanding in state of putting it in the bakes, we measured the change of surface area in regular square, and the thickness of epidermis and dermis after punching the tissues from the control group and the expanded group.
After removal of the fully expanded tissue expander, we measured the thickness of dermis and epidermis at intervals of 2 weeks for the 6 weeks.
The results were as follows.
1. The surface area of the expanded skin was increased, on an average, 38.64 % in comparison with the area of control skin(p<0.05).
2. When the tissues expanders were fully expanded for 6 weeks, the thickness of epidermis in the expanded group, 117.91±2.23um, became thicker than that of the control group, 91.68 ±2.47um and the thickness of dermis in the expanded gruop, 3003±117.84um, became thinner than that of the c^ntrol group, 3475±223.38um(p<0.05).
3. After 6 weeks following removal of the fully expaneded expanders, the thickness of epidermis.
|